Principal Manufacturing Associate
ImmaticsJoin Immatics and shape the future of cancer immunotherapy; one patient at a time!
Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.
Why Join Us?
Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
Global Impact: Contribute to therapies that make a lasting impact on patients globally.
We are seeking a Principal Manufacturing Associate to support our CMC-GMP team. This individual will provide direct leadership and oversight for the on-the-floor operations of cell therapy manufacturing in a cGMP environment.
FLSA Classification: Salary/ Exempt
Schedule: 8:00am - 5:00pm; Monday to Friday; On-site
Reports to: Manufacturing Manager
Location: 13203 Murphy Road Suite 100 Stafford, TX 77477; UTH GMP Facility at 1941 East Rd., Houston, TX 77054
What You’ll Do:
As a Principal Manufacturing Associate, you will play a key role in supporting our CMC-GMP operations:
Knowledge and adherence to cGMP requirements.
Provide leadership, guidance, and necessary training to staff in alignment with cGMP requirements and established procedures
Provide instruction to facilitate workflow, shift activities, and shift exchange ensuring all activities are completed as assigned.
Provide a safe and controlled work environment.
Provide deviation workflow support, including, but not limited to initiating, investigating, and troubleshooting deviations and unexpected events.
Serve as backup for manufacturing associates for daily manufacturing processes.
Review executed batch records and documents.
Coordinate with the Training Department to include training needs on the manufacturing schedule.
Clear communication with outgoing and incoming shift Leads and Managers to disseminate all relevant information.
Collaborate with the MSAT/PD teams to transfer new projects into GMP.
Develop or update internal policies, procedures or steps, identifies and escalate risks, communicates changes and plan for execution.
Leads routine team meetings and huddles.
Ability to work productively and to participate in a highly creative and fast-paced environment.
Secondary Functions:
Support scheduling and assignment of manufacturing activities.
Determines required corrective actions resulting from deviations or CAPAs and develop implementation plans. Acts as CAPA lead when required.
Reviews and ensure completion of all manufacturing-related logs.
Required Experience and Education:
Biomanufacturing Technology Associate of Applied Science Degree, Biomanufacturing Technology Level 2 Certificate, or equivalent. or an Associate degree in Biology, Biochemistry, Biotechnology, Biomanufacturing or another related field.
Seven (7) or more years of cell therapy manufacturing experience, or four (4) to five (5) years of cell therapy manufacturing experience combined with lead or supervisory experience.
Preferred Experience and Education:
Master’s Degree in Biology, Biochemistry, Biotechnology, Healthcare Administration or other related field.
Seven (7) years of cell therapy manufacturing experience.
Competencies:
Independent Working- no active supervision for routine tasks; minimal supervision on non-standard tasks.
Communication- advanced verbal communication; clear and efficient written communication; common courtesy; regular interaction with other teams or departments; basic presentation skills (efficient presentation of own work to small groups/own team).
Problem Solving- ability to identify, deeply analyze and communicate problems; advanced ability to develop and implement solutions within own area of responsibility.
Critical Thinking- advanced reflection on standard and non-standard processes; timely identification of need and room for improvement within own/narrow scope; ability to anticipate future risks; basic understanding and consideration of interfaces beyond own/narrow scope.
Initiative- high degree of initiative and intrinsic motivation to exceed basic expectations of own tasks and responsibilities; pro-active contribution to development of the team structure and lab processes (beyond own tasks).
Organizational & Prioritization Skills- advanced organizational skills required to structure work schedules beyond own daily tasks according to (and beyond) predefined work packages for standard and non-standard lab processes; deep understanding of priorities within own/narrow scope; prioritization requires minimal interaction with the manager.
Coachability- actively reflect on and suggest trainings supporting professional development within or beyond current area of responsibility; high responsiveness to constructive criticism and ability to autonomously reflect on required improvements and propose self-improvements; timely implementation of suggested improvements.
Leadership Skills, Training & Supervision- basic leadership skills required for on-the-job trainings and guidance/support of (new) team members (e.g. providing and receiving feedback, empathy, honesty, reliability); train, instruct and coordinate E level; train D level in specific area of expertise; train C level during onboarding.
Work Environment:
Typical office environment with moderate noise levels (~20% of work hours).
Uses phone, computer, office equipment and supplies on a regular basis.
cGMP clean room spaces and facilities (~80% of work hours).
Grade A/B/C/D GMP environment with associated facility noise levels.
Uses cleanroom phone, computer, variety of equipment and reagent/supplies.
General unclassified laboratory spaces, as needed.
Common laboratory equipment and noise levels.
While performing the duties of this job, the employee routinely handles blood components and is occasionally exposed to temperatures between -196°C and 40°C, liquid nitrogen, liquid nitrogen vapor, dry ice, and carbon dioxide.
Travel required: Travel may be required between the office building and manufacturing facility on a daily basis.
Physical demands:
Carrying: to transport an object – usually by holding it in the hands or arms but may occur on the shoulder.
Climbing: moving up or down step stools or ladders while maintaining balance.
Communicating Verbally: expressing or exchanging ideas by means of the spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately, loudly, or quickly.
Feeling: the ability to detect different materials or temperatures with fingers and hands.
Gowning: sitting or standing to don or remove sterile PPE.
Hearing: the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds.
Typing: entering data or text into a computer or other machine by means of a keyboard. Devices include a traditional keyboard, 10 key-pad, touch screens and others.
Lifting: raising or lowering an object (up to 25 lbs.) from one level to another (includes upward pulling).
Near Visual Acuity: clarity of vision at approximately 20 inches or less (working with small objects, reading small print, including the use of computers).
Undergo and pass a color blindness evaluation and assessment of vision abilities required for this position.
Pushing: Exerting force upon an object so that the object moves away from the object. Must be able to push carts and gas tanks on rolling wheels (approximately 50 lbs.).
Pulling: Exerting force upon an object so that the object moves toward the force. Must be able to pull carts and gas tanks on rolling wheels (approximately 50 lbs.).
Reaching: Extending both hands and/or arms perpendicular to the floor and in front of your body towards an object for extended periods of time.
Sitting: remaining in a sitting position for at least 50% of the time.
Standing/Walking: remain on one's feet in an upright position at a workstation.
Stooping: occasional bending the body downward and forward by bending the spine at the waist - requiring full use of the lower extremities and back muscle.
Work authorization/security clearance requirements :
Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment.
Affirmative Action/EEO statement:
Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs. We do not discriminate on the basis of race, color, religion, national origin, ethnicity, marital status, age, physical or mental disability, medical conditions, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.”
What do we offer?
At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics
Comprehensive Benefits:
Competitive rates for Health, Dental, and Vision Insurance
4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment.
Sick Time Off – 56 hours
12 Paid Holidays
100% Employer-Paid Life Insurance up to at 1x annual salary
100% Employer Paid Short- and Long-Term Disability Coverage
401(k) with Immediate Eligibility & company match…
You are eligible for 401(k) plan participation as of your first paycheck.
The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
Partially paid Parental Leave for eligible employees. (3 weeks)
Additional voluntary employee paid coverages including Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance.
Professional Growth:
Opportunities to work with leading experts in the field of T-cell immunotherapy.
Company provided learning and development opportunities
Fast paced, high demand collaborative and dynamic environment.